Review Comment:
Summary
The paper presents MatKG and HeLiFit, an integrated solution for scalable construction of a knowledge graph in digital healthcare. These tools aim to solve the challenge of data interoperability in healthcare by merging diverse data sources such as electronic medical records (EMR), medical devices, wearables, and consumer data. The system uses standards like FHIR and RML to build a cross-organization health data space, enabling AI-powered health recommendations.
Strengths
1. This paper presents a highly integrated and scalable pipeline (MatKG) for managing and processing heterogeneous data sources in digital healthcare. This is essential for overcoming the challenges of data interoperability across healthcare institutions and consumer technologies, which is a pressing issue in modern digital health.
2. The adoption of well-known standards such as FHIR and RML for data integration and semantic interoperability is a major strength. These standards ensure that the system can integrate various data sources in a way that aligns with industry practices, providing a foundation for broader adoption and scalability.
3. The paper emphasizes the practical application of the system across diverse healthcare institutions and patient cohorts in 11 countries. This demonstrates that the solution is not just theoretical but has been validated in real-world settings, with thousands of users involved in the pilot programs.
Weaknesses
1. The download address of EMR data and PHR data should be clearly given in the paper or Github, so that the data can be obtained more quickly.
2. The paper identifies limitations in the reasoning approach, particularly in the use of crisp thresholds for activity classification. This type of binary logic may not be suitable for all cases and could limit the system's adaptability to more nuanced patient conditions or dynamic health behaviors. The system might be too rigid in interpreting complex, real-time health data.
3. While using validated clinical guidelines for recommendation generation is a strength, this approach may also limit flexibility. The system could be more innovative if it incorporated real-time patient-specific data, rather than relying heavily on predefined clinical rules, which could be too general or rigid for personalized care.
4. While the paper mentions that the system has been piloted, there is a lack of specific evaluation metrics or performance benchmarks to demonstrate the effectiveness of the system. For example, how do the recommendations compare to current digital healthcare solutions in terms of accuracy, user satisfaction, or health outcomes?
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